Product Name

Tolazoline

CAS Number

59-98-3

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Product Name:
Tolazoline
CAS Number:
59-98-3
Indication:
For the treatment of pulmonary artery anomalies
Mode of Action:

Vasodilation by means of a direct effect on peripheral vascular smooth muscle and indirect effects produced, in part, by release of endogenous histamine; tolazoline has moderate alpha-adrenergic blocking activity and has histamine agonist activity. Tolazoline usually reduces pulmonary arterial pressure and vascular resistance.

Pharmacodynamics:

Tolazoline is a pulmonary vasodilator indicated used to decrease pulmonary vascular resistance (PVR) in persistent pulmonary hypertension of the newborn (PPHN).

IUPAC:
2-benzyl-4, 5-dihydro-1H-imidazole
ATC:
C04AB02 M02AX02
PubChem:
5504
DrugBank:
DB00797 (APRD00170)
Formula:
C14H11NO5
Molecular Mass:
160.2157
SMILES:
C(C1=NCCN1)C1=CC=CC=C1
InChi:
JIVZKJJQOZQXQB-UHFFFAOYSA-N

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