Product Name

Tetrabenazine

Name: Tetrabenazine - LGM Pharma
SKU: 58-46-8

CAS Number

58-46-8

LGM Pharma is an API distributor. LGM Pharma supplies APIs as per CGMP with DMF support, subject to availability and manufacturer requirements. LGM Pharma does not sell or supply APIs or finished dosage products to individual patients, doctors, or pharmacies.

Questions? Call our customer API support number 1-(800)-881-8210

Product Name:

Tetrabenazine

CAS Number:

58-46-8

Indication:

For the symptomatical treatment of hyperkinetic movement disorder.

Mode of Action:

Tetrabenazine works mainly as a VMAT-inhibitor and as such promotes the early metabolic degradation of the neurotransmitter dopamine. Dopamine is required for fine motor movement, so the inhibition of its transmission can lessen the effects of any hyperkinetic movement.

Metabolism:

CYP2D6 mediated hepatic metabolism.

IUPAC:

9, 10-dimethoxy-3-(2-methylpropyl)-1H, 2H, 3H, 4H, 6H, 7H, 11bH-pyrido[2, 1-a]isoquinolin-2-one

ATC:

N07XX06

PubChem:

6018

DrugBank:

DB04844

Formula:

C₇H₈N₄O₂

Molecular Mass:

317.4226

Synonyms:

Tetra benazin Tetrabenazina [inn-spanish] Tetrabenazinum [inn-latin] Tetrabenzaine Tetrabenzine

SMILES:

COC1=C(OC)C=C2C3CC(=O)C(CC(C)C)CN3CCC2=C1

InChi:

MKJIEFSOBYUXJB-UHFFFAOYSA-N

General Reference:

Jankovic J, Beach J: Long-term effects of tetrabenazine in hyperkinetic movement disorders. Neurology. 1997 Feb;48(2):358-62. Pubmed

Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1). Any patent infringement and resulting liability is solely at buyer risk.

LGM currently offers Monoclonal Antibodies (mAbs) for non-GMP/R&D use. Please inquire about Monoclonal Antibodies produced under GMP conditions.

Questions? Call our customer API support number 1-(800)-881-8210.

Ask us about this product

API’s From Quality Manufacturers:

Streamlined API supply towards initial research stages as well as larger quantities of cGMP material for clinical trials and product commercialization
Premium quality GMP certified and fully accredited API manufacturing plants
Technical packages as well as access to filed DMF, ASMF or CEP (subject to availability)
Regulatory and technical assistance towards any submission type based on specific customer requirements

Tetrabenazine

58-46-8

Ask us about this product

API’s From Quality Manufacturers:

Find an API Product