Product Name

Tetrabenazine

Name: Tetrabenazine - LGM Pharma
SKU: 58-46-8

CAS Number

58-46-8

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Product Name:

Tetrabenazine

CAS Number:

58-46-8

Indication:

For the symptomatical treatment of hyperkinetic movement disorder.

Mode of Action:

Tetrabenazine works mainly as a VMAT-inhibitor and as such promotes the early metabolic degradation of the neurotransmitter dopamine. Dopamine is required for fine motor movement, so the inhibition of its transmission can lessen the effects of any hyperkinetic movement.

Metabolism:

CYP2D6 mediated hepatic metabolism.

IUPAC:

9, 10-dimethoxy-3-(2-methylpropyl)-1H, 2H, 3H, 4H, 6H, 7H, 11bH-pyrido[2, 1-a]isoquinolin-2-one

ATC:

N07XX06

PubChem:

6018

DrugBank:

DB04844

Formula:

C₇H₈N₄O₂

Molecular Mass:

317.4226

Synonyms:

Tetra benazin Tetrabenazina [inn-spanish] Tetrabenazinum [inn-latin] Tetrabenzaine Tetrabenzine

SMILES:

COC1=C(OC)C=C2C3CC(=O)C(CC(C)C)CN3CCC2=C1

InChi:

MKJIEFSOBYUXJB-UHFFFAOYSA-N

General Reference:

Jankovic J, Beach J: Long-term effects of tetrabenazine in hyperkinetic movement disorders. Neurology. 1997 Feb;48(2):358-62. Pubmed

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Tetrabenazine

58-46-8

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