Product Name

Tenoxicam

Name: Tenoxicam - LGM Pharma
SKU: 59804-37-4

CAS Number

59804-37-4

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Product Name:

Tenoxicam

CAS Number:

59804-37-4

Indication:

For the treatment of rheumatoid arthritis, osteoarthritis, backache, and pain.

Mode of Action:

The antiinflammatory effects of tenoxicam may result from the inhibition of the enzyme cycooxygenase and the subsequent peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, their inhibition accounts for the peripheral analgesic effects of tenoxicam. Antipyresis may occur by central action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat loss.

Pharmacodynamics:

Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.

Metabolism:

Tenoxicam is metabolized in the liver to several pharmacologically inactive metabolites (mainly 5'-hydroxy-tenoxicam).

IUPAC:

(3Z)-3-{hydroxy[(pyridin-2-yl)amino]methylidene}-2-methyl-2H, 3H, 4H-1$l, {6}, 5, 2-thieno[2, 3-e][1$l, {6}, 2]thiazine-1, 1, 4-trione

ATC:

M01AC02

PubChem:

5282194

DrugBank:

DB00469 (APRD00011)

Formula:

C₂₆H₃₁Cl₂N₅O₃

Molecular Mass:

337.374

Synonyms:

Tenoxicamum [INN-Latin]

SMILES:

CN1C(=C(/O)NC2=CC=CC=N2)C(=O)C2=C(C=CS2)S1(=O)=O

AHFS Code:

28:08.04.92

InChi:

WZWYJBNHTWCXIM-RAXLEYEMSA-N

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Tenoxicam

59804-37-4

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