Product Name

Quazepam

CAS Number

36735-22-5

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Product Name:
Quazepam
CAS Number:
36735-22-5
Indication:
Used to treat insomnia.
Mode of Action:

Benzodiazepines bind nonspecifically to benzodiazepine receptors, which affects muscle relaxation, anticonvulsant activity, motor coordination, and memory. As benzodiazepine receptors are thought to be coupled to gamma-aminobutyric acid-A (GABAA) receptors, this enhances the effects of GABA by increasing GABA affinity for the GABA receptor. Binding of the inhibitory neurotransmitter GABA to the site opens the chloride channel, resulting in a hyperpolarized cell membrane that prevents further excitation of the cell.

Pharmacodynamics:

Quazepam is a benzodiazepine derivative. The main pharmacological action of quazepam is the enhancement of the neurotransmitter, GABA at the GABAA receptor.

Metabolism:

Hepatic.

IUPAC:
7-chloro-5-(2-fluorophenyl)-1-(2, 2, 2-trifluoroethyl)-2, 3-dihydro-1H-1, 4-benzodiazepine-2-thione
ATC:
N05CD10
PubChem:
4999
DrugBank:
DB01589
Formula:
C21H22N4O6S
Molecular Mass:
386.794
Synonyms:
Quazepamum [inn-latin]
SMILES:
FC1=CC=CC=C1C1=NCC(=S)N(CC(F)(F)F)C2=C1C=C(Cl)C=C2
InChi:
IKMPWMZBZSAONZ-UHFFFAOYSA-N

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