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Probucol

  • # LGM Pharma is a Probucol CAS# 23288-49-5 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, samples, sourcing, purity and more.
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  • # LGM Pharma offers this active ingredient but not the finished dosage forms.
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Product Details:

  • Product Name: Probucol
  • CAS #: 23288-49-5
  • Mode of Action:

    Probucol lowers serum cholesterol by increasing the fractional rate of low-density lipoprotein (LDL) catabolism in the final metabolic pathway for cholesterol elimination from the body. Additionally, probucol may inhibit early stages of cholesterol biosynthesis and slightly inhibit dietary cholesterol absorption. Recent information suggests that probucol may inhibit the oxidation and tissue deposition of LDL cholesterol, thereby inhibiting atherogenesis. It appears to inhibits ABCA1-mediated cellular lipid efflux.

  • Pharmacodynamics:

    Probucol lowers the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism. Additionally, probucol may inhibit cholesterol synthesis and delay cholesterol absorption. Probucol is a powerful antioxidant drug normally used to prevent vascular disease caused by the free radicals in the body.

  • IUPAC: 2, 6-di-tert-butyl-4-({2-[(3, 5-di-tert-butyl-4-hydroxyphenyl)sulfanyl]propan-2-yl}sulfanyl)phenol
  • ATC: C10AX02
  • PubChem: 4912
  • DrugBank: DB01599
  • Formula: C21H30O2
  • Molecular Mass: 516.842
  • Synonyms: 4,4'- (Isopropylidenedithio)bis(2, 6-di-tert-butylphenol) 4,4'-(Isopropylidenedithio)bis(2, 6-di-tert-butylphenol) 4,4'-(Isopropylidenedithio)bis(2,6-di-tert-butylphenol) 4,4'-(Isopropylidenedithio)bis[2, 6-di-tert-butylphenol] Acetone bis(3,5-di-tert-butyl-4-hydroxyphenyl) mercaptole Acetone, bis (3,5-di-tert-butyl-4-hydroxyphenyl) mercaptole Acetone, bis(3,5-di-tert-butyl-4-hydroxyphenyl) mercaptole Probucolum [inn-latin]
  • SMILES: CC(C)(SC1=CC(=C(O)C(=C1)C(C)(C)C)C(C)(C)C)SC1=CC(=C(O)C(=C1)C(C)(C)C)C(C)(C)C
  • AHFS Code: 24:06.9
  • InChl: FYPMFJGVHOHGLL-UHFFFAOYSA-N
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