Product Name

Prilocaine

CAS Number

721-50-6

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Product Name:
Prilocaine
CAS Number:
721-50-6
Indication:
Used as a local anaesthetic and is often used in dentistry.
Mode of Action:

Prilocaine acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation. The antiarrhythmic actions are mediated through effects on sodium channels in Purkinje fibers.

Pharmacodynamics:

Prilocaine binds to the intracellular surface of sodium channels which blocks the subsequent influx of sodium into the cell. Action potential propagation and never function is, therefore, prevented. This block is reversible and when the drug diffuses away from the cell, sodium channel function is restored and nerve propagation returns.

IUPAC:
N-(2-methylphenyl)-2-(propylamino)propanamide
ATC:
N01BB04
PubChem:
4906
DrugBank:
DB00750 (APRD00180)
Formula:
C16H22N2O3
Molecular Mass:
220.3107
SMILES:
CCCNC(C)C(=O)NC1=CC=CC=C1C
AHFS Code:
12:00.0
InChi:
MVFGUOIZUNYYSO-UHFFFAOYSA-N

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