• # LGM Pharma is a Prednisone CAS# 53-03-2 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, samples, sourcing, purity and more.
  • # Questions? Call our customer API support number 1-(800)-881-8210.
  • # LGM Pharma offers this active ingredient but not the finished dosage forms.
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Product Details:

  • Product Name: Prednisone
  • CAS #: 53-03-2
  • Mode of Action:

    Prednisone is a glucocorticoid receptor agonist. It is first metabolized in the liver to its active form, prednisolone. Prednisolone crosses cell membranes and binds with high affinity to specific cytoplasmic receptors. The result includes inhibition of leukocyte infiltration at the site of inflammation, interference in the function of mediators of inflammatory response, suppression of humoral immune responses, and reduction in edema or scar tissue. The antiinflammatory actions of corticosteroids are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes.

  • Pharmacodynamics:

    Prednisone, the most commonly-prescribed corticosteroid, is used to treat allograft rejection, asthma, systemic lupus erythematosus, and many other inflammatory states. Prednisone has very little mineralocorticoid activity.

  • Metabolism:

    Hepatic.

  • IUPAC: (1S, 2R, 10S, 11S, 14R, 15S)-14-hydroxy-14-(2-hydroxyacetyl)-2, 15-dimethyltetracyclo[8.7.0.0, {2, 7}.0, {11, 15}]heptadeca-3, 6-diene-5, 17-dione
  • ATC: A07EA03 H02AB07 H02AB15
  • PubChem: 5865
  • DrugBank: DB00635 (APRD00340)
  • Formula: C12H19N3O
  • Molecular Mass: 358.4281
  • Synonyms: Dehydrocortisone Prednisona [INN-Spanish] Prednisonum [INN-Latin]
  • SMILES: C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
  • AHFS Code: 08:04.0
  • InChl: XOFYZVNMUHMLCC-ZPOLXVRWSA-N
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1). Any patent infringement and resulting liability is solely at buyer risk.

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LGM Pharma Acquires CDMO

On July 27, 2020, LGM Pharma announced its acquisition of the formulation development and drug product contract manufacturing business of Nexgen Pharma, Inc. As a result, you will notice our new logo and visuals throughout the website. We’re working on updates to reflect the exciting, expanded CDMO capabilities and services we now can offer you.

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