LGM Pharma is an API distributor. LGM Pharma supplies APIs as per CGMP with DMF support, subject to availability and manufacturer requirements. LGM Pharma does not sell or supply APIs or finished dosage products to individual patients, doctors, or pharmacies.
Questions? Call our customer API support number 1-(800)-881-8210
Obeticholic Acid’s mechanism of action is unique as it acts as a hepatoprotective agent against a wide range of chronic liver diseases.
Obeticholic Acid is a semi-synthetic derivative of bile acid and works by adhering to a receptor in the liver, thus changing the metabolism of lipids in the body. As a natural agonist of the farnesoid X receptor, Obeticholic Acid acts as a nuclear hormone receptor which regulates lipid metabolism and glucose, thus decreasing hepatic steatosis and insulin resistance.
Obeticholic Acid In vitro acts as a powerful farnesoid X receptor agonist in HuH7 cells. In vivo Obeticholic Acid protects against acute necrosis, protects hepatocytes, reduces renal inflammation and oxidative stress and improves proteinuria.
Obeticholic Acid has not shown toxicity and the main adverse effect noted by patients is mild itching.
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1). Any patent infringement and resulting liability is solely at buyer risk.
LGM currently offers Monoclonal Antibodies (mAbs) for non-GMP/R&D use. Please inquire about Monoclonal Antibodies produced under GMP conditions.
Questions? Call our customer API support number 1-(800)-881-8210.