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Neostigmine Methylsulfate

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  • # LGM Pharma is a Neostigmine Methylsulfate CAS# 51-60-5 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, samples, sourcing, purity and more.
  • # Questions? Call our customer API support number 1-(800)-881-8210.
  • # LGM Pharma offers this active ingredient but not the finished dosage forms.
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Product Details:

  • Product Name: Neostigmine Methylsulfate
  • CAS #: 51-60-5
  • Metabolism:

    Neostigmine is destroyed by plasma esterases, and the quaternary alcohol and parent compound are excreted in the urine.

  • IUPAC: [3-(dimethylcarbamoyloxy)phenyl]-trimethylazanium;methyl sulfate
  • PubChem: 5824
  • DrugBank: DB01400
  • Formula: C13H22N2O6S
  • Molecular Mass: 334.119858 g/mol
  • Synonyms: (m-Hydroxyphenyl)trimethylammonium dimethylcarbamate, 3-Trimethylammoniumphenyl N,N-dimethylcarbamate, Eustigmin, Eustigmine, m-Trimethylammoniumphenyldimethylcarbamate, Neostigmina
  • SMILES: CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C.COS(=O)(=O)[O-]
  • AHFS Code: 12:04.00 — Parasympathomemetic (Cholinergic) Agents
  • InChl: InChI=1S/C12H19N2O2.CH4O4S/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5;1-5-6(2,3)4/h6-9H,1-5H3;1H3,(H,2,3,4)/q+1;/p-1
  • Product Description:

    Neostigmine methyl sulfate is an arylammonium sulfate salt. It has a role as an EC 3.1.1.8 (cholinesterase) inhibitor. A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.

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