Product Name

Neostigmine Methylsulfate

CAS Number

51-60-5

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Product Name:

Neostigmine Methylsulfate

CAS Number:

51-60-5

Metabolism:

Neostigmine is destroyed by plasma esterases, and the quaternary alcohol and parent compound are excreted in the urine.

IUPAC:

[3-(dimethylcarbamoyloxy)phenyl]-trimethylazanium;methyl sulfate

PubChem:

5824

DrugBank:

DB01400

Formula:

C13H22N2O6S

Molecular Mass:

334.119858 g/mol

Synonyms:

(m-Hydroxyphenyl)trimethylammonium dimethylcarbamate, 3-Trimethylammoniumphenyl N,N-dimethylcarbamate, Eustigmin, Eustigmine, m-Trimethylammoniumphenyldimethylcarbamate, Neostigmina

SMILES:

CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C.COS(=O)(=O)[O-]

AHFS Code:

12:04.00 — Parasympathomemetic (Cholinergic) Agents

InChi:

InChI=1S/C12H19N2O2.CH4O4S/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5;1-5-6(2,3)4/h6-9H,1-5H3;1H3,(H,2,3,4)/q+1;/p-1

Product Description:

Neostigmine methyl sulfate is an arylammonium sulfate salt. It has a role as an EC 3.1.1.8 (cholinesterase) inhibitor. A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.

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Neostigmine Methylsulfate

51-60-5

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