Product Name

Neostigmine Methylsulfate

CAS Number

51-60-5

LGM Pharma is an API distributor. LGM Pharma can supply CGMP and/or DMF products, subject to availability and manufacturer requirements. LGM Pharma does not sell or supply APIs or finished dosage products to individual patients, doctors, pharmacies, or any pharmaceutical companies.

Questions? Call our customer API support number 1-(800)-881-8210

Product Name:

Neostigmine Methylsulfate

CAS Number:

51-60-5

Metabolism:

Neostigmine is destroyed by plasma esterases, and the quaternary alcohol and parent compound are excreted in the urine.

IUPAC:

[3-(dimethylcarbamoyloxy)phenyl]-trimethylazanium;methyl sulfate

PubChem:

5824

DrugBank:

DB01400

Formula:

C13H22N2O6S

Molecular Mass:

334.119858 g/mol

Synonyms:

(m-Hydroxyphenyl)trimethylammonium dimethylcarbamate, 3-Trimethylammoniumphenyl N,N-dimethylcarbamate, Eustigmin, Eustigmine, m-Trimethylammoniumphenyldimethylcarbamate, Neostigmina

SMILES:

CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C.COS(=O)(=O)[O-]

AHFS Code:

12:04.00 — Parasympathomemetic (Cholinergic) Agents

InChi:

InChI=1S/C12H19N2O2.CH4O4S/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5;1-5-6(2,3)4/h6-9H,1-5H3;1H3,(H,2,3,4)/q+1;/p-1

Product Description:

Neostigmine methyl sulfate is an arylammonium sulfate salt. It has a role as an EC 3.1.1.8 (cholinesterase) inhibitor. A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.

Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1). Any patent infringement and resulting liability is solely at buyer risk.

LGM currently offers Monoclonal Antibodies (mAbs) for non-GMP/R&D use. Please inquire about Monoclonal Antibodies produced under GMP conditions.

Questions? Call our customer API support number 1-(800)-881-8210.

Ask us about this product

API’s From Quality Manufacturers:

Streamlined API supply towards initial research stages as well as larger quantities of cGMP material for clinical trials and product commercialization
Premium quality GMP certified and fully accredited API manufacturing plants
Technical packages as well as access to filed DMF, ASMF or CEP (subject to availability)
Regulatory and technical assistance towards any submission type based on specific customer requirements

Neostigmine Methylsulfate

51-60-5

Ask us about this product

API’s From Quality Manufacturers:

Find an API Product