Product Name

Methoxsalen

CAS Number

298-81-7

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Product Name:
Methoxsalen
CAS Number:
298-81-7
Indication:
For the treatment of psoriasis and vitiligo
Mode of Action:

After activation it binds preferentially to the guanine and cytosine moieties of DNA, leading to cross-linking of DNA, thus inhibiting DNA synthesis and function.

Pharmacodynamics:

Methoxsalen selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of Methoxsalen-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed.

IUPAC:
9-methoxy-2H-furo[3, 2-g]chromen-2-one
ATC:
D05AD02 D05BA02
PubChem:
4114
DrugBank:
DB00553 (APRD00157)
Formula:
C23H36O6
Molecular Mass:
216.1895
Synonyms:
Methoxalen Xanthotoxin Xanthotoxine Xanthoxin Zanthotoxin
SMILES:
COC1=C2OC(=O)C=CC2=CC2=C1OC=C2
AHFS Code:
24:50.1
InChi:
QXKHYNVANLEOEG-UHFFFAOYSA-N

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Questions? Call our customer API support number 1-(800)-881-8210. 

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