0532-03-06 Category:
  • # LGM Pharma is a Methocarbamol CAS# 0532-03-06 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, samples, sourcing, purity and more.
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  • # LGM Pharma offers this active ingredient but not the finished dosage forms.
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Product Details:

  • Product Name: Methocarbamol
  • CAS #: 0532-03-06
  • Mode of Action:

    The mechanism of action of methocarbamol in humans has not been established, but may be due to central nervous system depression. It has no direct action on the contractile mechanism of striated muscle, the motor end plate or the nerve fiber.

  • Pharmacodynamics:

    Methocarbamol is a central muscle relaxant for skeletal muscles, used to treat spasms. It is structurally related to guaifenesin. Methocarbamol's exact mechanism of causing skeletal muscle relaxation is unknown. It is thought to work centrally, perhaps by general depressant effects. It has no direct relaxant effects on striated muscle, nerve fibers, or the motor endplate. It will not directly relax contracted skeletal muscles. The drug has a secondary sedative effect.

  • Metabolism:


  • Toxicity:

    Symptoms of overdose include blurred vision, coma, drowsiness, low blood pressure, nausea, and seizures.

  • General Reference:

    1. Sica DA, Comstock TJ, Davis J, Manning L, Powell R, Melikian A, Wright G: Pharmacokinetics and protein binding of methocarbamol in renal insufficiency and normals. Eur J Clin Pharmacol. 1990;39(2):193-4. Pubmed

  • IUPAC: 2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate
  • ATC: M03BA03
  • PubChem: 4107
  • DrugBank: DB00423 (APRD01102)
  • Formula: C20H30O2
  • Molecular Mass: 241.2405
  • AHFS Code: 12:20.0
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