Product Name

Maralixibat

CAS Number

716313-53-0

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Product Name:
Maralixibat
CAS Number:
716313-53-0
IUPAC:
(4R,5R)-5-[4-[[4-(4-aza-1-azoniabicyclo[2.2.2]octan-1-ylmethyl)phenyl]methoxy]phenyl]-3,3-dibutyl-7-(dimethylamino)-1,1-dioxo-4,5-dihydro-2H-1λ6-benzothiepin-4-ol
ATC:
A05AX04
PubChem:
9831643
DrugBank:
DB16226
Formula:
C40H56N3O4S+
Molecular Mass:
675
InChi:
InChi
Product Description:

Maralixibat is an orally available inhibitor of the ileal bile salt transporter which is used to treat severe pruritus in patients with cholestatic liver disease including Alagille syndrome without cirrhosis. Maralixibat is associated with transient serum enzyme fluctuations particularly with long term therapy but has not been linked to instances of clinically apparent liver injury with jaundice, although experience with its use has been limited.

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