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Lubiprostone

  • # LGM Pharma is a Lubiprostone CAS# 136790-76-6 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, samples, sourcing, purity and more.
  • # Questions? Call our customer API support number 1-(800)-881-8210.
  • # LGM Pharma offers this active ingredient but not the finished dosage forms.
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Product Details:

  • Product Name: Lubiprostone
  • CAS #: 136790-76-6
  • Mode of Action:

    Lubiprostone is a bicyclic fatty acid (prostaglandin E1 derivative) that acts by specifically activating ClC-2 chloride channels on the apical aspect of gastrointestinal epithelial cells, producing a chloride-rich fluid secretion. These secretions soften the stool, increase motility, and promote spontaneous bowel movements (SBM). Symptoms of constipation (pain, bloating) are usually improved within one week, and SBM may occur within one day.

  • IUPAC: 7-[(1R, 3R, 6R, 7R)-3-(1, 1-difluoropentyl)-3-hydroxy-8-oxo-2-oxabicyclo[4.3.0]non-7-yl]heptanoic acid
  • ATC: A06AX03
  • PubChem: 157920
  • DrugBank: APRD01298
  • Formula: C20H32O5
  • Molecular Mass: 390.462
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1). Any patent infringement and resulting liability is solely at buyer risk.

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