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Fosfomycin Tromethamine

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  • # LGM Pharma is a Fosfomycin Tromethamine CAS# 78964-85-9 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, samples, sourcing, purity and more.
  • # Questions? Call our customer API support number 1-(800)-881-8210.
  • # LGM Pharma offers this active ingredient but not the finished dosage forms.
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Product Details:

  • Product Name: Fosfomycin Tromethamine
  • CAS #: 78964-85-9
  • IUPAC: [1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]azanium;hydroxy-[(2R,3S)-3-methyloxiran-2-yl]phosphinate
  • PubChem: 54331
  • Formula: C7H18NO7P
  • Molecular Mass: 259.19 g/mol
  • Synonyms: Fosfomycin, Fosfomycin Trometamol Salt, fosfomycin tromethamine, Monuril, Phosphomycin, Phosphonomycin, Tromethamine, Fosfomycin
  • SMILES: CC1C(O1)P(=O)(O)[O-].C(C(CO)(CO)[NH3+])O
  • InChl: InChI=1S/C4H11NO3.C3H7O4P/c5-4(1-6,2-7)3-8;1-2-3(7-2)8(4,5)6/h6-8H,1-3,5H2;2-3H,1H3,(H2,4,5,6)/t;2-,3+/m.0/s1
  • Product Description:

    Fosfomycin trometamol (fosfomycin tromethamine) is approved in numerous countries worldwide, mainly for the treatment of uncomplicated urinary tract infections (UTIs). Fosfomycin has good in vitro activity against common uropathogens, such as Escherichia coli (including extended-spectrum β-lactamase-producing E. coli), Proteus mirabilis, Klebsiella pneumoniae and Staphylococcus saprophyticus, and the susceptibility of uropathogens to fosfomycin has remained relatively stable over time. A single oral dose of fosfomycin trometamol 3 g (the approved dosage) achieves high concentrations in urine.

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