Product Name

Ferric Carboxymaltose

CAS Number

9007-72-1

LGM Pharma is an API distributor. LGM Pharma can supply CGMP and/or DMF products, subject to availability and manufacturer requirements. LGM Pharma does not sell or supply APIs or finished dosage products to individual patients, doctors, pharmacies, or any pharmaceutical companies.

Questions? Call our customer API support number 1-(800)-881-8210

Product Name:
Ferric Carboxymaltose
CAS Number:
9007-72-1
Indication:
Ferric carboxymaltose is a iron replacement product indicated for the treatment of iron deficiency anemia in adult patients who have intolerance to oral iron or have had unsatisfactory response to oral iron or those who have non-dialysis dependent chronic kidney disease.
Mode of Action:

Ferric carboxymaltose is a colloidal iron (III) hydroxide in complex with carboxymaltose, a carbohydrate polymer that release iron.

Pharmacodynamics:

When measured using positron emission tomography (PET), the red cell uptake of 59-Fe and 52-Fe from INJECTAFER ranged from 61% to 99%. In patients with iron deficiency, the red cell uptake ranged from 91% to 99%. In patients with renal anemia, the red cell uptake ranged from 61% to 84%.

Toxicity:

The most common adverse reactions (>2%) are nausea, hypertension, flushing, hypophosphatemia, and dizziness.

IUPAC:
Iron(3+) hydroxide oxide poly-(1->4)-alpha-D-glucopyranosyl-(1->4)-D-gluconate hydrate
DrugBank:
DB08917
Molecular Mass:
788.4316
Synonyms:
Ferinject Ferric carboxymaltose Injectafer Iron Dextri-Maltose Polynuclear iron (III)-hydroxide 4(R)-(poly-(1->4)-O-alpha-D-glucopyranosyl)-oxy- 2(R),3(S),5(R), 6-tetrahydroxy-hexanoate UNII-6897GXD6OE VIT 45 VIT-45
AHFS Code:
20:04.0
General Reference:
General Reference:

FDA label

Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1). Any patent infringement and resulting liability is solely at buyer risk.

LGM currently offers Monoclonal Antibodies (mAbs) for non-GMP/R&D use. Please inquire about Monoclonal Antibodies produced under GMP conditions.

Questions? Call our customer API support number 1-(800)-881-8210. 

Ask us about this product

API’s From Quality Manufacturers:

  • Streamlined API supply towards initial research stages as well as larger quantities of cGMP material for clinical trials and product commercialization
  • Premium quality GMP certified and fully accredited API manufacturing plants
  • Technical packages as well as access to filed DMF, ASMF or CEP (subject to availability)
  • Regulatory and technical assistance towards any submission type based on specific customer requirements

Find an API Product

SEARCH
Generic filters