Product Name

Dexlansoprazole

CAS Number

138530-94-6

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Product Name:
Dexlansoprazole
CAS Number:
138530-94-6
Indication:
Investigated for use/treatment in duodenal ulcers, gastric ulcers, gastroesophageal reflux disease (GERD), and gastrointestinal diseases and disorders (miscellaneous).
Mode of Action:

Lansoprazole has an asymmetric sulfur in its chemical structure and is commercially marketed as a racemic mixture. Both the (R)- and (S)-enantiomers of lansoprazole inhibit acid formation in isolated canine parietal cells and (H'+'/K'+')-ATPase in canine gastric microsomes with nearly the same potency.

IUPAC:
1H-Benzimidazole, 2-((R)-((3-methyl-4-(2, 2, 2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-
ATC:
A02BC06
DrugBank:
DB05351
Formula:
C16-H14-F3-N3-O2-S
Molecular Mass:
369.3656
Synonyms:
(+)-2-((R)-{(3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl}sulfinyl)-1H-benzimidazole, 2-((R)-((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole, Dexilant, Dexlansoprazole, Kapidex, T 168390, T-168390, TAK 390, TAK-390, UNII-UYE4T5I70X
SMILES:
Cc1c(ccnc1C[S@@](=O)c2[nH]c3ccccc3n2)OCC(F)(F)F
InChi:
1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22)/t25-/m1/s1

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