Product Name

Carbimazole

Name: Carbimazole - LGM Pharma
SKU: 22232-54-8

CAS Number

22232-54-8

LGM Pharma is an API distributor. LGM Pharma can supply CGMP and/or DMF products, subject to availability and manufacturer requirements. LGM Pharma does not sell or supply APIs or finished dosage products to individual patients, doctors, pharmacies, or any pharmaceutical companies.

Questions? Call our customer API support number 1-(800)-881-8210

Product Name:

Carbimazole

CAS Number:

22232-54-8

Indication:

For the treatment of hyperthyroidism and thyrotoxicosis. It is also used to prepare patients for thyroidectomy.

Mode of Action:

Carbimazole is an aitithyroid agent that decreases the uptake and concentration of inorganic iodine by thyroid, it also reduces the formation of di-iodotyrosine and thyroxine. Once converted to its active form of methimazole, it prevents the thyroid peroxidase enzyme from coupling and iodinating the tyrosine residues on thyroglobulin, hence reducing the production of the thyroid hormones T3 and T4.

Pharmacodynamics:

Carbimazole is a carbethoxy derivative of methimazole. Its antithyroid action is due to its conversion to methimazole after absorption. It is used to treat hyperthyroidism and thyrotoxicosis.

IUPAC:

ethyl 3-methyl-2-sulfanylidene-2, 3-dihydro-1H-imidazole-1-carboxylate

ATC:

H03BB01

PubChem:

31072

DrugBank:

DB00389 (APRD00503)

Formula:

C₁₄H₁₉Cl₂NO₂

Molecular Mass:

186.232

Synonyms:

Athyromazole Carbethoxymethimazole Carbimazol Carbimazol [INN-Spanish, French] Carbimazolum [INN-Latin] Carbinazole

SMILES:

CCOC(=O)N1C=CN(C)C1=S

InChi:

CFOYWRHIYXMDOT-UHFFFAOYSA-N

Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1). Any patent infringement and resulting liability is solely at buyer risk.

LGM currently offers Monoclonal Antibodies (mAbs) for non-GMP/R&D use. Please inquire about Monoclonal Antibodies produced under GMP conditions.

Questions? Call our customer API support number 1-(800)-881-8210.

Ask us about this product

API’s From Quality Manufacturers:

Streamlined API supply towards initial research stages as well as larger quantities of cGMP material for clinical trials and product commercialization
Premium quality GMP certified and fully accredited API manufacturing plants
Technical packages as well as access to filed DMF, ASMF or CEP (subject to availability)
Regulatory and technical assistance towards any submission type based on specific customer requirements

Carbimazole

22232-54-8

Ask us about this product

API’s From Quality Manufacturers:

Find an API Product