Product Name

Bromfenac sodium

Name: Bromfenac sodium - LGM Pharma
SKU: 91714-93-1

CAS Number

91714-93-1

LGM Pharma is an API distributor. LGM Pharma can supply CGMP and/or DMF products, subject to availability and manufacturer requirements. LGM Pharma does not sell or supply APIs or finished dosage products to individual patients, doctors, pharmacies, or any pharmaceutical companies.

Questions? Call our customer API support number 1-(800)-881-8210

Product Name:

Bromfenac sodium

CAS Number:

91714-93-1

Indication:

For the treatment of postoperative inflammation in patients who have undergone cataract extraction.

Mode of Action:

The mechanism of its action is thought to be due to its ability to block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2. Prostaglandins have been shown in many animal models to be mediators of certain kinds of intraocular inflammation. In studies performed in animal eyes, prostaglandins have been shown to produce disruption of the blood-aqueous humor barrier, vasodilation, increased vascular permeability, leukocytosis, and increased intraocular pressure.

Pharmacodynamics:

Bromfenac ophthalmic solution is a sterile, topical, nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use.

IUPAC:

Benzeneacetic acid, 2-amino-3-(4-bromobenzoyl)-, monosodium salt

ATC:

S01BC11

DrugBank:

DB00963

Formula:

C15-H12-Br-N-O3.Na

Molecular Mass:

356.1499

Synonyms:

AHR 10282B, Bromfenac sodium, Bromsite, Bronuck, UNII-9X8YF771OU

SMILES:

c1cc(c(c(c1)C(=O)c2ccc(cc2)Br)N)CC(=O)[O-].[Na+]

InChi:

1S/C15H12BrNO3.Na/c16-11-6-4-9(5-7-11)15(20)12-3-1-2-10(14(12)17)8-13(18)19;/h1-7H,8,17H2,(H,18,19);/q;+1/p-1

Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1). Any patent infringement and resulting liability is solely at buyer risk.

LGM currently offers Monoclonal Antibodies (mAbs) for non-GMP/R&D use. Please inquire about Monoclonal Antibodies produced under GMP conditions.

Questions? Call our customer API support number 1-(800)-881-8210.

Ask us about this product

API’s From Quality Manufacturers:

Streamlined API supply towards initial research stages as well as larger quantities of cGMP material for clinical trials and product commercialization
Premium quality GMP certified and fully accredited API manufacturing plants
Technical packages as well as access to filed DMF, ASMF or CEP (subject to availability)
Regulatory and technical assistance towards any submission type based on specific customer requirements

Bromfenac sodium

91714-93-1

Ask us about this product

API’s From Quality Manufacturers:

Find an API Product