Product Name

Berotralast Hydrochloride

CAS Number

1809010-52-3

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Product Name:
Berotralast Hydrochloride
CAS Number:
1809010-52-3
IUPAC:
2-[3-(aminomethyl)phenyl]-N-[5-[(R)-(3-cyanophenyl)-(cyclopropylmethylamino)methyl]-2-fluorophenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide;dihydrochloride
ATC:
B06AC06
PubChem:
139030242
DrugBank:
DBSALT003120
Formula:
C30H28Cl2F4N6O
Molecular Mass:
635.49
InChi:
InChi
Product Description:

Berotralstat is a selective inhibitor of plasma kallikrein used in the prophylaxis of attacks of hereditary angioedema (HAE). It works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE. Berotralstat is strictly used to prevent, but not treat, these attacks.

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