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Benzocaine

CAS No:
94-09-7 Category:
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Product Details:

  • Product Name: Benzocaine
  • CAS #: 94-09-7
  • Mode of Action:

    Benzocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions. Depolarization of the neuronal membrane is inhibited thereby blocking the initiation and conduction of nerve impulses.

  • Pharmacodynamics:

    Benzocaine is a local anesthetic commonly used as a topical pain reliever. It is the active ingredient in many over-the-counter analgesic ointments. It is also indicated for general use as a lubricant and topical anesthetic on intratracheal catheters and pharyngeal and nasal airways to obtund the pharyngeal and tracheal reflexes; on nasogastric and endoscopic tubes; urinary catheters; laryngoscopes; proctoscopes; sigmoidoscopes and vaginal specula.

  • Toxicity:

    LD50=3040 mg/kg (rat, oral)

  • IUPAC: ethyl 4-aminobenzoate
  • ATC: C05AD03 D04AB04 N01BA05 R02AD01 A01AD11
  • PubChem: 2337
  • DrugBank: DB01086 (APRD00539)
  • Formula: C23H28N2O3
  • Molecular Mass: 165.1891
  • Synonyms: Ethyl Aminobenzoate Ethyl P-Aminobenzoate Ethyl P-Aminophenylcarboxylate Ethylester Kyseliny P-Aminobenzoove P-Aminobenzoic Acid, Ethyl Ester P-Carbethoxyaniline P-Ethoxycarboxylic Aniline
  • SMILES: CCOC(=O)C1=CC=C(N)C=C1
  • AHFS Code: 52:16.00 84:08.00
  • InChl: BLFLLBZGZJTVJG-UHFFFAOYSA-N
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