Product Name

Amlodipine Besylate

CAS Number


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Product Name:
Amlodipine Besylate
CAS Number:
Mode of Action:

L-type calcium channel blocker that displays antihypertensive properties. Inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease. Inhibits proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells (IC50 = 25 μM).

2-[(2-Aminoethoxy)methyl]-4-(2-chlo rophenyl)-1, 4-dihydro-6-methyl-3, 5-pyridinedicarbo xylic acid 3-ethyl 5-methyl ester benzenesulfonate
Molecular Mass:
2-[(2-AMINOETHOXY)-METHYL]-4-(2-CHLOROPHENYL)-1,4-DIHYDRO-6-METHYL-3,5-PYRIDINEDICARBOXYLIC ACID 3-ETHYL 5-METHYL ESTER BENZENE SULFONATE, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine benzenesulfonate, AMLODIPINE BENZENESULFONATE, AMLODIPINE BESILATE, AMLODIPINE BESYLATE, NORVASC, 3,5-pyridinedicarboxylicacid,2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1, 4-dihydro-6-methyl-,3-ethyl-5-methylester,monobenzenesulfonate, AMLODIPINE BESILATE MM(CRM STANDARD), AMLODIPINE BESYLATE EPY(CRM STANDARD), 2-[(2-aminoethoxy)-methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzene sulfonate, AMLODIPINEBESYLATE(SUBJECTTOPATENTFREE), (+-)-3-Ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate monobenzenesulfonate, 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, monobenzenesulfonate, Amcard, Amdepin, Amdipin, Amlodin, Amlopin, Amlor
General Reference:
General Reference:
  1. Arrowsmith, J.E., et al. 1986. J. Med. Chem. 29: 1696-1702. PMID: 2943898
  2. Burges, R.A., et al. 1987. J. Cardiovasc. Pharmacol. 9: 110-119. PMID: 2434785
  3. Packer, M., et al. 1996. N. Engl. J. Med. 335: 1107-1114. PMID: 8813041
  4. Yoshida, J., et al. 2003. Eur. J. Pharmacol. 472: 23-31. PMID: 12860469
  5. Toba, H., et al. 2005 Hypertens. Res. 28: 689-700. PMID: 16392774

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