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Amisulpride

CAS No:
71675-85-9 Category:
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Product Details:

  • Product Name: Amisulpride
  • CAS #: 71675-85-9
  • Mode of Action:

    Amisulpride binds selectively to dopamine D(2) and D(3) receptors in the limbic system. Low doses of amisulpride preferentially block presynaptic D(2)/D(3)-dopamine autoreceptors, thereby enhancing dopaminergic transmission, whereas higher doses block postsynaptic receptors, thus inhibiting dopaminergic hyperactivity. It may also have 5-ht7 antagonistic effect, useful in depression treatment.

  • Toxicity:

    Overdoses of amisulpride have been linked with torsades de pointes.

  • IUPAC: 4-amino-5-(ethanesulfonyl)-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxybenzamide
  • ATC: N05AL05
  • PubChem: 2159
  • DrugBank: DB06288
  • Formula: C38H52N6O7
  • Molecular Mass: 369.479
  • Synonyms: Aminosultopride
  • SMILES: CCN1CCCC1CNC(=O)C1=CC(=C(N)C=C1OC)S(=O)(=O)CC
  • InChl: NTJOBXMMWNYJFB-UHFFFAOYSA-N
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