Browsing tag:

serotonin


migrane

Sumatriptan CAS #: 103628-46-2 Sumatriptan is an API that works with the serotonin neurons in the brain to fight migraines and cluster headaches. By constricting the blood vessels in the brain back to their normal size and preventing the trigeminal nerve from firing at full force, sumatriptan is designed to stop symptoms as soon as they start.[…]

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Known as the brand name migraine treatment Axert, marketed by Ortho-McNeil Pharmaceuticals, Almotriptan’s patent protection expires in May 2015. This is exciting news for research and development teams who are currently seeking to provide migraine sufferers with additional therapies. Almotriptan, or Axert, is currently FDA approved to treat migraine with or without aura in adults[…]

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On January 5, 2015 Jubilant Life Sciences received an FDA nod for their Rizatriptan generic formulation, paving the way for more generic forms of Merck’s blockbuster migraine medication Maxalt. The strengths approved for generic production are both 5 milligrams and 10 milligrams, which makes up an estimated 70 million dollar market. Rizatriptan is an efficacious[…]

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Encouraging news from The Lancet was published in mid-November 2013 regarding the use of Pimavanserin to alleviate Parkinson’s Psychosis. Data from a successful phase 3 trial was revealed and strongly touted the use of Pimavanserin for psychotic symptoms as related to Parkinson’s disease. Pimavanserin is effectual at blocking serotonin 5-HT2A receptors, which are often associated[…]

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The approval of Vortioxetine CAS# 508233-74-7 came as exciting news at the close of September 2013. Known as the brand name Brintellix, Vortioxetine is marketed by Lundbeck and Takeda Pharmaceuticals. The FDA approval of this antidepressant is encouraging for both patients suffering from Major Depressive Disorder and the practitioners who treat these patients, as Vortioxetine[…]

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Levomilnacipran, CAS number 96847-55-1, has been a headline in the recent pharmaceutical news. This headline status is due to the FDA approval of Fetzima, the brand name for Levomilnacipran, at the end of July 2013. Approved as a medication to treat major depressive disorder in adults, Levomilnacipran is designed as a once daily dose. As[…]

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The expiration for the patent of the new formulation of Prozac, also known as the generic drug Fluoxetine Hydrochloride, is slated for November 1, 2017. As a common and effectual antidepressant, Fluoxetine HCl CAS# 56296-78-7, has proven to be a valuable treatment for patients in the United States and worldwide. In fact, antidepressant use in[…]

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Vilazodone is in a class of medications called selective serotonin reuptake inhibitors, or SSRIs, and is also a 5HT1A receptor partial agonist. Known as the brand name Viibryd, this medication was approved in January of 2011 to treat Major Depressive Disorder in adults. In safety studies involving 2,177 patients the most common adverse side effects[…]

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Paroxetine Hydrochloride, known by the trade name Paxil, has an upcoming patent expiration date of May 19, 2015. As a well used medication to treat depression, Paroxetine HCl, CAS number 78246-49-8, is projected to become a generic powerhouse. Paroxetine is efficacious at treating not only major depression, but also obsessive compulsive disorder, panic disorder, social[…]

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Duloxetine Hydrochloride CAS# 136434-34-9, is also known as the brand name Cymbalta marketed by Lilly. This effective antidepressant will be going off patent in June of 2013. Duloxetine hydrochloride is currently approved to treat the following: clinical depression; peripheral diabetic neuropathy pain, or nerve pain in the hands, feet, arms, and legs from diabetes; generalized[…]

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