The most common form of hyperthyroidism in the US is Graves Disease. In the recent months, it has seen a promising alternative to surgery and radioactive iodine therapy in the form of the drug, methimazole. Methimazole is an anti-thyroid drug that is usually given to patients prior to undergoing surgical thyroid removal in order to[…]
Methimazole provides a good alternative to surgery and radiation in Graves disease therapy
Bulk Active Ingredient Tags: LDL Sep 20, 2011
Epirubicin improves HER2-positive breast cancer survival
Chemotherapeutic / Anti-Neoplastic, Drug Research & Development API Tags: Anthracyclinesbreast cancercancer treatment Sep 13, 2011
In the recent decades, women’s health has taken center stage. No longer hidden in obscurity, breast cancer emerged as a growing concern for women all over the world. The disease does not just strike women, it affects children and men as well, albeit indirectly. The role of the woman as a mom and earning partner[…]
Monotherapy with Darunavir is Where the "MONET" is
Anti-Retroviral / Anti-HIV, Drug Research & Development API Tags: AIDSDarunavir EthanolateHIVHIV virusRitonavir Sep 02, 2011
AIDS is a global pandemic whose cure has eluded scientists and doctors for more than 2 decades. Acquired immunodeficiency syndrome (AIDS) is caused by the Human Immunodeficiency Virus (HIV) which progressively undermines the strength of the immune system until such a time that the body becomes incapable of fighting off infections and vulnerable to opportunistic[…]
Paricalcitol is Still the Best First Line Treatment for Secondary Hyperparathyroidism (SHPT)
Drug Research & Development API Tags: hypocalcemiavitamin D Aug 08, 2011
Secondary hyperparathyroidism (SHPT) is a common complication associated with chronic renal failure. The damaged kidneys do not convert enough vitamin D to its active form, calciferol, and inadequately excrete phosphate. This results in the formation of insoluble calcium phosphate in the body and removal of calcium from the blood circulation. Both processes lead to hypocalcemia,[…]
Report Shows Antibiotic Resistant Gonorrhea Increase
Antibiotic, Bulk Active Ingredient, Drug Research & Development API Tags: antibioticCDC Aug 03, 2011
Gonorrhea is a sexually transmitted disease (STD) caused by the bacterium Neisseria Gonorrhoeae. Gonorrhea is a very common infectious disease among the sexually active young adults and teens. The Center for Disease Control and Prevention (CDC) estimates that more than 700,000 persons in the U.S. acquire the infection yearly. Unlike HIV, exchange of body fluids[…]
Prostaglandins: What are they and how do they work?
Glossary, Prostaglandin Tags: prostaglandin Jul 13, 2011
A prostaglandin is any member of a group of lipid compounds that are derived enzymatically from fatty acids and have important functions in the animal body. Every prostaglandin contains 20 carbon atoms, including a 5-carbon ring. They are mediators and have a variety of strong physiological effects, such as regulating the contraction and relaxation of[…]
Temsirolimus Combo Therapy Increases Cancer Remission
Chemotherapeutic / Anti-Neoplastic, Drug Research & Development API, Immunosuppressant Tags: acute myeloid leukemiaAnnual Meetingcancer treatmentchemotherapy Jun 21, 2011
Over the past decade, pharmaceutical firms have been giving oncologists the choice to combine several drugs used in cancer treatment in order to battle even the most resistant of cancer cells. This move has been proven successful in some types of cancer, prompting pharmaceutical manufacturers to supply consistent, quality-controlled active pharmaceutical ingredients (API’s), such as[…]
Everolimus shoots two very different birds with one stone; cancer cells and coronary stents
Drug Research & Development API, Immunosuppressant Tags: 159351-69-6Everolimuskinase inhibitor Jun 08, 2011
In 2009 a new anti-cancer drug, Everolimus, was approved in the US and Europe specifically for use in patients with advanced kidney cancer who were unresponsive to the standard chemotherapy regimen. As a kinase inhibitor, Everolimus effectively inhibits cancer cells from dividing. Since then, the use of Everolimus has extended to treatment of subependymal giant[…]
Toremifene in the prevention and treatment of prostate cancer
Chemotherapeutic / Anti-Neoplastic, Drug Research & Development API Tags: breast cancerprostate cancer Jun 03, 2011
Although not brand new, Toremifene has been found to be as effective as Tamoxifen, in breast cancer, as a selective estrogen receptor modulator (SERM) with the added advantage of better patient tolerability and lesser adverse effects. Several drugs for this specific type of cancer have been developed but only a handful has made it to[…]
Elacridar – A Unique Delivery System Fighting Chemotherapy Resistance
Chemotherapeutic / Anti-Neoplastic, Drug Research & Development API Tags: cancer treatmentchemotherapyDocetaxelimatinibIrinotecanPaclitaxel Jun 03, 2011
Elacridar, an ABCB1 modulator acting as a drug transporter, has been proven to have beneficial effects on the resistance of cancer cells to standard chemotherapeutic agents. This unique delivery system makes resistant cancers more susceptible to standard chemotherapeutic regimen. A study done by Ho Lun Wong et al showed beneficial results when Elacridar was used[…]
