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Anti-Fungal


Amphotericin B

Amphotericin B: CAS No: 1397-89-3 Amphotericin B is an API used to treat a number of fungal infections. This pharmaceutical ingredient is aggressive when interacting with the fungus which is why it’s generally used for serious cases only. However, it’s also proven itself to be one of the most effective ways to stop the spread[…]

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Anidulafungin

Anidulafungin CAS No: 166663-25-8 Anidulafungin is an antifungal API used to combat general yeast infections found in the blood, stomach, or esophagus and some varieties of Aspergillus. As an echinocandin, it inhibits the growth of fungal cell walls which results in either fungal cell instability or death. Echinocandins are unique in that they affect the[…]

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Posaconazole

Posaconazole CAS No:171228-49-2 Posaconazole is a type of oral triazole antifungal API that has shown a high rate of efficacy for a number of fungal conditions without the risk of severe side effects. While many antifungal medications have ostensibly similar jobs, each one has their own limitations and patient disadvantages. Posaconazole was developed as an[…]

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Dermatological Antifungal

The dermatological antifungal segment has three more FDA approved options. This is good news for a specialty area that could use more diversity when it comes to treating fungal infections. Tavaborole and Efinaconazole were both approved by the FDA in 2014 to treat fungi of the nail and nailbeds, and Crisaborole was approved in 2016[…]

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Exciting news was shared in the January 2015 issue of Mycoses, with clinical data revealing that the use of Caspofungin to treat invasive fungal disease in leukemia patients was both positive and responsive. Adult patients who were diagnosed with acute lymphoblastic leukemia attained relief from their suspected fungal disease after the clinical use of Caspofungin.[…]

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As the fourth most common cause of hospital-acquired bloodstream infections in the United States, Invasive Candidiasis is a concern for any patient battling a fungal infection. Micafungin, also known as the brand name Mycamine, which is marketed by Astellas, is an effective antifungal agent. By inhibiting the synthesis of 1,3-beta-D-glucan, Micafungin proves to be a[…]

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Anacor Pharmaceuticals, Inc. ANAC, announced on Jul 08, 2014 that the FDA has approved the New Drug Application for Tavaborole, which is marketed as KERYDIN™ topical solution, 5%. Tavaborole was designed to be convenient for patients to use and it’s the first oxaborole antifungal approved for the topical treatment of onychomycosis of the toenails. Onychomycosis[…]

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Butoconazole Nitrate, CAS number 64872-77-1 is also known as the brand name GYNAZOLE-1. Marketed by Ther-Rx Corporation, the patent for this vaginal cream expires November 17, 2017. Indicated for the treatment of vulvovaginal candidiasis, or infections caused by Candida, butoconazole is available in a 2% strength cream. Statistically Candida, or yeast infections, are extremely common.[…]

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