Tolazoline

CAS No:
59-98-3 Category:
  • #LGM Pharma is a Tolazoline CAS# 59-98-3 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, delivery, purity, and more.
  • #Questions? Call our customer API support number 1-(800)-881-8210.
  • #LGM Pharma offers this active ingredient but not the finished dosage forms.

Product Details:

  • CAS No: 59-98-3
  • AHFC code:
  • Synonyms:
  • ATC Code: C04AB02 M02AX02
  • Chemical Formula: C14H11NO5
  • Molecular Weight: 160.2157
  • Assay/Purity: Typically NLT 98%
  • DrugBank: DB00797 (APRD00170)
  • SMILES: C(C1=NCCN1)C1=CC=CC=C1
  • InChl: JIVZKJJQOZQXQB-UHFFFAOYSA-N
  • PubChem: 5504
  • IUPAC: 2-benzyl-4,5-dihydro-1H-imidazole

Additional Details

Indication:
For the treatment of pulmonary artery anomalies
Pharmacodynamics:
Tolazoline is a pulmonary vasodilator indicated used to decrease pulmonary vascular resistance (PVR) in persistent pulmonary hypertension of the newborn (PPHN).
Mode of Action:
Vasodilation by means of a direct effect on peripheral vascular smooth muscle and indirect effects produced, in part, by release of endogenous histamine; tolazoline has moderate alpha-adrenergic blocking activity and has histamine agonist activity. Tolazoline usually reduces pulmonary arterial pressure and vascular resistance.
Metabolism:
Toxicity:
General Reference:
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1). Any patent infringement and resulting liability is solely at buyer risk.

API’s From Quality Manufacturers:

  • Cost effective materials based on specific requirements
  • Small quantities for initial research and larger development quantities towards product commercialization

 

  • Technical packages, letters of access to filed DMFs
  • Complete assistance in any regulatory filings
  • Top quality GMP certified manufacturers
  • Have necessary regulatory credentials

 

Related YouTube Videos