LGM Pharma is a Tolazoline CAS# 59-98-3 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, delivery, purity, and more.
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LGM Pharma offers this active ingredient but not the finished dosage forms.
CAS No: 59-98-3
ATC Code: C04AB02 M02AX02
Chemical Formula: C14H11NO5
Molecular Weight: 160.2157
Assay/Purity: Typically NLT 98%
DrugBank: DB00797 (APRD00170)
For the treatment of pulmonary artery anomalies
Tolazoline is a pulmonary vasodilator indicated used to decrease pulmonary vascular resistance (PVR) in persistent pulmonary hypertension of the newborn (PPHN).
Mode of Action:
Vasodilation by means of a direct effect on peripheral vascular smooth muscle and indirect effects produced, in part, by release of endogenous histamine; tolazoline has moderate alpha-adrenergic blocking activity and has histamine agonist activity. Tolazoline usually reduces pulmonary arterial pressure and vascular resistance.
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