26652-09-5 Category:
  • #LGM Pharma is a Ritodrine CAS# 26652-09-5 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, delivery, purity, and more.
  • #Questions? Call our customer API support number 1-(800)-881-8210.
  • #LGM Pharma offers this active ingredient but not the finished dosage forms.

Product Details:

  • CAS No: 26652-09-5
  • AHFC code:
  • Synonyms: Ritodrina [INN-Spanish] Ritodrine Hcl Ritodrine Hydrochloride Ritodrinium [INN-Latin]
  • ATC Code: G02CA01
  • Chemical Formula: C16H24N2O
  • Molecular Weight: 287.3535
  • Assay/Purity: Typically NLT 98%
  • DrugBank: DB00867 (APRD00541)
  • SMILES: C[C,H](NCCC1=CC=C(O)C=C1)[C,H](O)C1=CC=C(O)C=C1
  • PubChem: 33572
  • IUPAC: 4-[(1R,2S)-1-hydroxy-2-{[2-(4-hydroxyphenyl)ethyl]amino}propyl]phenol

Additional Details

For the treatment and prophylaxis of premature labour
Beta-2 adrenergic receptors are located at sympathetic neuroeffector junctions of many organs, including uterus. Ritodrine is beta-2 adrenergic agonist. It stimulates beta-2 adrenergic receptor, increases cAMP level and decreases intracellular calcium concentration. The decrease of calcium concentration leads to a relaxation of uterine smooth muscle and, therefore, a decrease in premature uterine contractions.
Mode of Action:
Ritodrine is beta-2 adrenergic agonist. It binds to beta-2 adrenergic receptors on outer membrane of myometrial cell, activates adenyl cyclase to increase the level of cAMP which decreases intracellular calcium and leads to a decrease of uterine contractions.
Hepatic, by both the mother and fetus
LD50=64mg/kg (mice, IV); LD50=540 mg/kg (mice, oral); LD50=85 mg/kg (rat, IV)
General Reference:
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1). Any patent infringement and resulting liability is solely at buyer risk.

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