3595-11-7 Category:
  • #LGM Pharma is a Propylhexedrine CAS# 11/7/95 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, delivery, purity, and more.
  • #Questions? Call our customer API support number 1-(800)-881-8210.
  • #LGM Pharma offers this active ingredient but not the finished dosage forms.

Product Details:

  • CAS No: 11/7/95
  • AHFC code:
  • Synonyms: (+-)-N,alpha-Dimethylcyclohexaneethylamine, (Cyclohexaneethyl)amine, N-alpha-dimethyl-, 1-Cyclohexyl-2-(methylamino)propane, 1-Cyclohexyl-2-methylaminopropan, 1-Cyclohexyl-2-methylaminopropan [German], 1-Cyclohexyl-N-methyl-2-propanamine, 3-12-00-00108 (Beilstein Handbook Reference), Benzedrex, beta-Cyclohexyl-isopropylmethylamin, beta-Cyclohexyl-isopropylmethylamin [German], BRN 3194303, CHP-Depot, Cyclohexaneethanamine, N,alpha-dimethyl-, (+-)-, Dristan, Dristan Inhaler, EINECS 202-939-3, EINECS 222-741-0, Hexahydrodesoxyephedrine, Hydromethamphetamine, Methyl-(1-methyl-2-cyclohexylethyl)amine, NSC 32410, Obesin, Obesine, Propilesedrina, Propilesedrina [DCIT], Propilhexedrina, Propilhexedrina [INN-Spanish], Propylhexedrin, Propylhexedrine, Propylhexedrinum, Propylhexedrinum [INN-Latin], UNII-LQU92IU8LL
  • ATC Code:
  • Chemical Formula: C10-H21-N
  • Molecular Weight: 155.2804
  • Assay/Purity: Typically NLT 98%
  • DrugBank: DB06714
  • InChl: 1S/C10H21N/c1-9(11-2)8-10-6-4-3-5-7-10/h9-11H,3-8H2,1-2H3
  • PubChem: 7558
  • IUPAC: Cyclohexaneethanamine, N,alpha-dimethyl-, (+-) Cyclohexaneethylamine, alpha,N-dimethyl- N,alpha-Dimethylcyclohexaneethylamine

Additional Details

It is used to provide temporary symptomatic relief of nasal congestion due to colds, allergies and allergic rhinitis.
Like other monoamine releasing stimulants propylhexedrine is active as a norepinephrine and dopamine releaser in the central nervous system. The acute effects of the drug closely resemble the physiological and psychological effects of an epinephrine-provoked fight-or-flight response, including increased heart rate and blood pressure, vasoconstriction (constriction of the arterial walls), bronchodilation, and hyperglycemia (increased blood sugar).
Mode of Action:
Propylhexidrine causes the norepinephrine, dopamine, and serotonin (5HT) transporters to reverse their direction of flow. This inversion leads to a release of these transmitters from the vesicles to the cytoplasm and from the cytoplasm to the synapse. It also antagonizes the action of VMAT2, causing the release of more neurotransmitters.
The signs and symptoms that are produced after the acute overdosage of Propylhexidrine include Psychosis, Burning sensation.
General Reference:
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1). Any patent infringement and resulting liability is solely at buyer risk.

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