721-50-6 Category:
  • #LGM Pharma is a Prilocaine CAS# 721-50-6 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, delivery, purity, and more.
  • #Questions? Call our customer API support number 1-(800)-881-8210.
  • #LGM Pharma offers this active ingredient but not the finished dosage forms.

Product Details:

  • CAS No: 721-50-6
  • AHFC code: 12:00.0
  • Synonyms:
  • ATC Code: N01BB04
  • Chemical Formula: C16H22N2O3
  • Molecular Weight: 220.3107
  • Assay/Purity: Typically NLT 98%
  • DrugBank: DB00750 (APRD00180)
  • PubChem: 4906
  • IUPAC: N-(2-methylphenyl)-2-(propylamino)propanamide

Additional Details

Used as a local anaesthetic and is often used in dentistry.
Prilocaine binds to the intracellular surface of sodium channels which blocks the subsequent influx of sodium into the cell. Action potential propagation and never function is, therefore, prevented. This block is reversible and when the drug diffuses away from the cell, sodium channel function is restored and nerve propagation returns.
Mode of Action:
Prilocaine acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation. The antiarrhythmic actions are mediated through effects on sodium channels in Purkinje fibers.
General Reference:
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1). Any patent infringement and resulting liability is solely at buyer risk.

API’s From Quality Manufacturers:

  • Cost effective materials based on specific requirements
  • Small quantities for initial research and larger development quantities towards product commercialization


  • Technical packages, letters of access to filed DMFs
  • Complete assistance in any regulatory filings
  • Top quality GMP certified manufacturers
  • Have necessary regulatory credentials


Related YouTube Videos