Pirenzepine

CAS No:
28797-61-7 Category:
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Product Details:

  • CAS No: 28797-61-7
  • AHFC code:
  • Synonyms:
  • ATC Code: A02BX03
  • Chemical Formula: C23H36O7
  • Molecular Weight: 351.4023
  • Assay/Purity: Typically NLT 98%
  • DrugBank: DB00670 (APRD00515)
  • SMILES: CN1CCN(CC(=O)N2C3=CC=CC=C3C(=O)NC3=C2N=CC=C3)CC1
  • InChl: RMHMFHUVIITRHF-UHFFFAOYSA-N
  • PubChem: 4848
  • IUPAC: 2-[2-(4-methylpiperazin-1-yl)acetyl]-2,4,9-triazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-10-one

Additional Details

Indication:
For the treatment of peptic ulcer, gastric ulcer, and duodenal ulcer.
Pharmacodynamics:
Pirenzepine belongs to a group of medications called antispasmodics/anticholinergics. These medications are used to relieve cramps or spasms of the stomach, intestines, and bladder. Pirenzepine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer. It may also be used to prevent nausea, vomiting, and motion sickness.
Mode of Action:
Pirenzepine is a muscarinic receptor antagonist and binds to the muscarinic acetylcholine receptor. The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.
Metabolism:
Toxicity:
General Reference:
Czepita D: [Fundamentals of modern treatment of myopia] Ann Acad Med Stetin. 2005;51(2):5-9. Pubmed
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