54-91-1 Category:
  • #LGM Pharma is a Pipobroman CAS# 54-91-1 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, delivery, purity, and more.
  • #Questions? Call our customer API support number 1-(800)-881-8210.
  • #LGM Pharma offers this active ingredient but not the finished dosage forms.

Product Details:

  • CAS No: 54-91-1
  • AHFC code:
  • Synonyms:
  • ATC Code: L01AX02
  • Chemical Formula: C171H267N51O53S2
  • Molecular Weight: 356.054
  • Assay/Purity: Typically NLT 98%
  • DrugBank: DB00236 (APRD00693)
  • PubChem: 4842
  • IUPAC: 3-bromo-1-[4-(3-bromopropanoyl)piperazin-1-yl]propan-1-one

Additional Details

For the treatment of polycythaemia vera and refractory chronic myeloid leukaemia.
Pipobroman is an antineoplastic agent. Specifically it is a piperazine derivative with a chemical structure close to that of many DNA alkylating agents. Pipobroman has well documented clinical activity against polycythemia vera and essential thrombocythemia.
Mode of Action:
The mechanism of action is uncertain but pipobroman is thought to alkylate DNA leading to disruption of DNA synthesis and eventual cell death.
Symptoms of overdose include hematologic toxicity, especially with chronic overdosage.
General Reference:
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1). Any patent infringement and resulting liability is solely at buyer risk.

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