Pentosan Polysulfate Sodium

CAS No:
116001-96-8 Categories: ,
  • #LGM Pharma is a Pentosan Polysulfate Sodium CAS# 116001-96-8 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, delivery, purity, and more.
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  • #LGM Pharma offers this active ingredient but not the finished dosage forms.

Product Details:

  • CAS No: 116001-96-8
  • AHFC code:
  • Synonyms: PPS
  • ATC Code: C05BA
  • Chemical Formula: C10H18O21S4
  • Molecular Weight: 602.49732
  • Assay/Purity: Typically NLT 98%
  • DrugBank:
  • SMILES:
  • InChl:
  • PubChem:
  • IUPAC:

Additional Details

Indication:
Pentosan Polysulfate Sodium is used to treat both bladder pain and discomfort in patients suffering from interstitial cystitis. Pentosan is available in 100 milligram capsules. Pentosan is also an anticoagulant that may be used to prevent blood clots from forming.
Pharmacodynamics:
Absorption- 3%, eliminates via urineMetabolism- Spleen and liverHalf-life- Approximately 4.8 hours
Mode of Action:
As a low-molecular weight heparinoid, Pentosan Polysulfate Sodium is believed to effectively treat interstitial cystitis by adhering to the mucosa of the bladder wall, buffering the tissues from possible irritating substances in the urine.
Metabolism:
Toxicity:
General Reference:
http://www.orthoelmiron.com/?utm_source=bing&utm_medium=cpc&utm_campaign=RAIS-Branded&utm_term=pentosan%20polysulfate&utm_content=Branded|mkwid|OlLv9ITa|pcrid|1094792061FDAPLoS One. 2014 Jun 25;9(6):e100882. doi: 10.1371/journal.pone.0100882. eCollection 2014.Mulholland SG, Hanno P, Parsons CL, Sant GR, Staskin DR "Pentosan polysulfate sodium for therapy of interstitial cystitis. A double-blind placebo-controlled clinical study." Urology 35 (1990): 552-8http://equimed.com/news/products/pentosan-polysulfate-effective-in-osteoarthritis-in-horses
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