Oxandrolone

CAS No:
53-39-4 Category:
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Product Details:

  • CAS No: 53-39-4
  • AHFC code:
  • Synonyms: Ossandrolone [DCIT] Oxandrolona [INN-Spanish] Oxandrolonum [INN-Latin]
  • ATC Code: A14AA08
  • Chemical Formula: C15H12N2O2
  • Molecular Weight: 306.4397
  • Assay/Purity: Typically NLT 98%
  • DrugBank: DB00621 (APRD01151)
  • SMILES: C[C,]1(O)CC[C,H]2[C,,H]3CC[C,H]4CC(=O)OC[C,]4(C)[C,H]3CC[C,]12C
  • InChl: QSLJIVKCVHQPLV-PEMPUTJUSA-N
  • PubChem: 5878
  • IUPAC: (1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,14,15-trimethyl-4-oxatetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-5-one

Additional Details

Indication:
Use to promote weight gain after weight loss following extensive surgery.
Pharmacodynamics:
Oxandrolone is an anabolic steroids indicated as adjunctive therapy to promote weight gain after weight loss following extensive surgery, chronic infections, or severe trauma, and in some patients who without definite pathophysiologic reasons fail to gain or to maintain normal weight, to offset the protein catabolism associated with prolonged administration of corticosteroids, and for the relief of the bone pain frequently accompanying osteoporosis. Anabolic steroids are synthetic derivatives of testosterone.
Mode of Action:
Oxandrolones interact with androgen receptors in target tissues.
Metabolism:
Renal
Toxicity:
The oral LD50 of oxandrolone in mice and dogs is greater than 5,000 mg/kg.
General Reference:
Demling RH, DeSanti L: Oxandrolone induced lean mass gain during recovery from severe burns is maintained after discontinuation of the anabolic steroid. Burns. 2003 Dec;29(8):793-7. Pubmed
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