35189-28-7 Category:
  • #LGM Pharma is a Norgestimate CAS# 35189-28-7 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, delivery, purity, and more.
  • #Questions? Call our customer API support number 1-(800)-881-8210.
  • #LGM Pharma offers this active ingredient but not the finished dosage forms.

Product Details:

  • CAS No: 35189-28-7
  • AHFC code:
  • Synonyms: Dexnorgestrel Acetime Norgestimato [INN-Spanish] Norgestimatum [INN-Latin]
  • ATC Code: G03AA11
  • Chemical Formula: C17H20N4S
  • Molecular Weight: 369.4971
  • Assay/Purity: Typically NLT 98%
  • DrugBank: DB00957 (APRD00569)
  • SMILES: CC[C,]12CC[C,H]3[C,,H](CCC4=CC(CC[C,H]34)=NO)[C,,H]1CC[C,,]2(OC(C)=O)C#C
  • PubChem: 6540478
  • IUPAC: (1S,2R,5E,10R,11S,14R,15S)-15-ethyl-14-ethynyl-5-(hydroxyimino)tetracyclo[^{2,7}.0^{11,15}]heptadec-6-en-14-yl acetate

Additional Details

For the prevention of pregnancy
Norgestimate is used as a female contraceptive. Norgestimate is a progestin or a synthetic form of the naturally occurring female sex hormone, progesterone. In a woman's normal menstrual cycle, an egg matures and is released from the ovaries (ovulation). The ovary then produces progesterone, preventing the release of further eggs and priming the lining of the womb for a possible pregnancy. If pregnancy occurs, progesterone levels in the body remain high, maintaining the womb lining. If pregnancy does not occur, progesterone levels in the body fall, resulting in a menstrual period. Norgestimate tricks the body processes into thinking that ovulation has already occurred, by maintaining high levels of the synthetic progesterone. This prevents the release of eggs from the ovaries.
Mode of Action:
Norgestimate binds to androgen and progestogen receptors. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Once bound to the receptor, progestins like Norgestimate will slow the frequency of release of gonadotropin releasing hormone (GnRH) from the hypothalamus and blunt the pre-ovulatory LH (luteinizing hormone) surge.
GI tract/Hepatic
General Reference:
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1). Any patent infringement and resulting liability is solely at buyer risk.

API’s From Quality Manufacturers:

  • Cost effective materials based on specific requirements
  • Small quantities for initial research and larger development quantities towards product commercialization


  • Technical packages, letters of access to filed DMFs
  • Complete assistance in any regulatory filings
  • Top quality GMP certified manufacturers
  • Have necessary regulatory credentials


Related YouTube Videos