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Monoclonal Antibodies (mAbs)
Monoclonal Antibodies (mAbs) Featured
LGM Pharma is a Ibritumomab Tiuxetan CAS# 206181-63-7 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, delivery, purity, and more.
Questions? Call our customer API support number 1-(800)-881-8210.
LGM Pharma offers this active ingredient but not the finished dosage forms.
BAY 86-5128, BAY86-5128, Ibritumomab, Ibritumomab tiuxetan, IDEC-129, IDEC-Y2B8, Immunoglobulin G1 (mouse monoclonal IDEC-Y2B8 gamma1-chain anti-human antigen CD20), disulfide with mouse monoclonal IDEC-Y2B8 K-chain, dimer, N-(2-(bis(carboxymethyl)amino)-3-(p-isothiocyanatophenyl)propyl)-N-(2-(bis(carboxymethyl)amino)propyl)glycine conjugate. Molecular weight is approximately 1500 daltons, SHL 749, UNII-4Q52C550XK, Zevalin
Typically NLT 98%
Immunoglobulin G1, anti-(human CD20 (antigen)) (mouse monoclonal IDEC-Y2B8 gamma1-chain), disulfide with mouse monoclonal IDEC-Y2B8 kappa-chain, dimer, N-(2-(bis(carboxymethyl)amino)-3-(4-isothiocyanatophenyl)propyl)-N-(2-(bis(carboxymethyl)amino)propyl)glycine conjugate
For treatment of non-Hodgkin’s lymphoma
Ibritumomab is a murine monoclonal antibody against CD20 that has been radiolabeled with yttrium-90.
Mode of Action:
The Fab segment of the antibody targets the CD20 epitope on B-cells, allowing the radioactive yttrium to destroy the cell via production of beta particles.
Most likely removed by opsonization via the reticuloendothelial system when bound to B cells, or by human antimurine antibody production
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1). Any patent infringement and resulting liability is solely at buyer risk.
API’s From Quality Manufacturers:
Cost effective materials based on specific requirements
Small quantities for initial research and larger development quantities towards product commercialization
Technical packages, letters of access to filed DMFs
Complete assistance in any regulatory filings
Top quality GMP certified manufacturers
Have necessary regulatory credentials
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