Epothilone D

  • #LGM Pharma is a Epothilone D CAS# 189453-10-9 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, delivery, purity, and more.
  • #Questions? Call our customer API support number 1-(800)-881-8210.
  • #LGM Pharma offers this active ingredient but not the finished dosage forms.

Product Details:

  • CAS No: 189453-10-9
  • AHFC code:
  • Synonyms: KOS-862
  • ATC Code:
  • Chemical Formula: C27H41NO5S
  • Molecular Weight: 491.683
  • Assay/Purity: Typically NLT 98%
  • DrugBank: DB01873 (EXPT01350)
  • SMILES: C[C,H]1CCCC(C)=C/C[C,,H](OC(=O)C[C,,H](O)C(C)(C)C(=O)[C,,H](C)[C,,H]1O)C(C)=CC1=CSC(C)=N1
  • InChl: XOZIUKBZLSUILX-UKMAFROXSA-N
  • PubChem:
  • IUPAC: (4R,7S,8R,9S,13Z,16R)-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-[(1E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclohexadec-13-ene-2,6-dione

Additional Details

Indication:
Pharmacodynamics:
Mode of Action:
The principal mechanism of the epothilone class is inhibition of microtubule function. Microtubules are essential to cell division, and epothilones therefore stop cells from properly dividing.
Metabolism:
Toxicity:
General Reference:
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1). Any patent infringement and resulting liability is solely at buyer risk.

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