Dexlansoprazole

  • #LGM Pharma is a Dexlansoprazole CAS# 138530-94-6 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, delivery, purity, and more.
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  • #LGM Pharma offers this active ingredient but not the finished dosage forms.

Product Details:

  • CAS No: 138530-94-6
  • AHFC code:
  • Synonyms: (+)-2-((R)-{(3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl}sulfinyl)-1H-benzimidazole, 2-((R)-((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole, Dexilant, Dexlansoprazole, Kapidex, T 168390, T-168390, TAK 390, TAK-390, UNII-UYE4T5I70X
  • ATC Code: A02BC06
  • Chemical Formula: C16-H14-F3-N3-O2-S
  • Molecular Weight: 369.3656
  • Assay/Purity: Typically NLT 98%
  • DrugBank: DB05351
  • SMILES: Cc1c(ccnc1C[S,,](=O)c2[nH]c3ccccc3n2)OCC(F)(F)F
  • InChl: 1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22)/t25-/m1/s1
  • PubChem:
  • IUPAC: 1H-Benzimidazole, 2-((R)-((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-

Additional Details

Indication:
Investigated for use/treatment in duodenal ulcers, gastric ulcers, gastroesophageal reflux disease (GERD), and gastrointestinal diseases and disorders (miscellaneous).
Pharmacodynamics:
Mode of Action:
Lansoprazole has an asymmetric sulfur in its chemical structure and is commercially marketed as a racemic mixture. Both the (R)- and (S)-enantiomers of lansoprazole inhibit acid formation in isolated canine parietal cells and (H'+'/K'+')-ATPase in canine gastric microsomes with nearly the same potency.
Metabolism:
Toxicity:
General Reference:
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1). Any patent infringement and resulting liability is solely at buyer risk.

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