456-59-7 Category:
  • #LGM Pharma is a Cyclandelate CAS# 456-59-7 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, delivery, purity, and more.
  • #Questions? Call our customer API support number 1-(800)-881-8210.
  • #LGM Pharma offers this active ingredient but not the finished dosage forms.

Product Details:

  • CAS No: 456-59-7
  • AHFC code:
  • Synonyms: 3,3,5-Trimethylcyclohexyl mandelate 3,5,5-Trimethylcyclohexyl amygdalate 3,5,5-Trimethylcyclohexyl mandelate Ciclandelato [inn-spanish] Cyclandelatum [inn-latin] Cyclandelic acid
  • ATC Code: C04AX01
  • Chemical Formula: C28H30N2O2
  • Molecular Weight: 276.3707
  • Assay/Purity: Typically NLT 98%
  • DrugBank: DB04838
  • PubChem: 2893
  • IUPAC: 3,3,5-trimethylcyclohexyl 2-hydroxy-2-phenylacetate

Additional Details

Used in the treatment of various blood vessel diseases (e.g., claudication, arteriosclerosis and Raynaud's disease) and nighttime leg cramps.
Cyclandelate is in a class of drugs called vasodilators. Cyclandelate relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily.
Mode of Action:
Cyclandelate produces peripheral vasodilation by a direct effect on vascular smooth muscle. Pharmacological action may be due to calcium-channel antagonism.
Acute oral toxicity (LD50): 3950 mg/kg [Guinea pig]
General Reference:
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1). Any patent infringement and resulting liability is solely at buyer risk.

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