Cyclandelate

CAS No:
456-59-7 Category:
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Product Details:

  • CAS No: 456-59-7
  • AHFC code:
  • Synonyms: 3,3,5-Trimethylcyclohexyl mandelate 3,5,5-Trimethylcyclohexyl amygdalate 3,5,5-Trimethylcyclohexyl mandelate Ciclandelato [inn-spanish] Cyclandelatum [inn-latin] Cyclandelic acid
  • ATC Code: C04AX01
  • Chemical Formula: C28H30N2O2
  • Molecular Weight: 276.3707
  • Assay/Purity: Typically NLT 98%
  • DrugBank: DB04838
  • SMILES: CC1CC(CC(C)(C)C1)OC(=O)C(O)C1=CC=CC=C1
  • InChl: WZHCOOQXZCIUNC-UHFFFAOYSA-N
  • PubChem: 2893
  • IUPAC: 3,3,5-trimethylcyclohexyl 2-hydroxy-2-phenylacetate

Additional Details

Indication:
Used in the treatment of various blood vessel diseases (e.g., claudication, arteriosclerosis and Raynaud's disease) and nighttime leg cramps.
Pharmacodynamics:
Cyclandelate is in a class of drugs called vasodilators. Cyclandelate relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily.
Mode of Action:
Cyclandelate produces peripheral vasodilation by a direct effect on vascular smooth muscle. Pharmacological action may be due to calcium-channel antagonism.
Metabolism:
Toxicity:
Acute oral toxicity (LD50): 3950 mg/kg [Guinea pig]
General Reference:
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1). Any patent infringement and resulting liability is solely at buyer risk.

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