Cinitapride

CAS No:
66564-14-5 Category:
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Product Details:

  • CAS No: 66564-14-5
  • AHFC code:
  • Synonyms:
  • ATC Code:
  • Chemical Formula: C4H6N4O3S2
  • Molecular Weight: 402.4873
  • Assay/Purity: Typically NLT 98%
  • DrugBank: DB08810
  • SMILES: CCOC1=CC(N)=C(C=C1C(=O)NC1CCN(CC2CCC=CC2)CC1)[N+]([O-])=O
  • InChl: ZDLBNXXKDMLZMF-UHFFFAOYSA-N
  • PubChem: 68867
  • IUPAC: 4-amino-N-[1-(cyclohex-3-en-1-ylmethyl)piperidin-4-yl]-2-ethoxy-5-nitrobenzamide

Additional Details

Indication:
For the treatment of gastrointestinal disorders associated with motility disturbances such as gastroesophageal reflux disease, non-ulcer dyspepsia and delayed gastric emptying.
Pharmacodynamics:
Mode of Action:
Cinitapride is a substituted benzamide with 5-HT receptor antagonist and agonist activity.
Metabolism:
Toxicity:
The symptoms of overdose include drowsiness, confusion and extrapyramidal effects.
General Reference:
Alarcon-de-la-Lastra Romero C, Lopez A, Martin MJ, la Casa C, Motilva V: Cinitapride protects against ethanol-induced gastric mucosal injury in rats: role of 5-hydroxytryptamine, prostaglandins and sulfhydryl compounds. Pharmacology. 1997 Apr;54(4):193-202. Pubmed
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