22232-54-8 Category:
  • #LGM Pharma is a Carbimazole CAS# 22232-54-8 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, delivery, purity, and more.
  • #Questions? Call our customer API support number 1-(800)-881-8210.
  • #LGM Pharma offers this active ingredient but not the finished dosage forms.

Product Details:

  • CAS No: 22232-54-8
  • AHFC code:
  • Synonyms: Athyromazole Carbethoxymethimazole Carbimazol Carbimazol [INN-Spanish, French] Carbimazolum [INN-Latin] Carbinazole
  • ATC Code: H03BB01
  • Chemical Formula: C14H19Cl2NO2
  • Molecular Weight: 186.232
  • Assay/Purity: Typically NLT 98%
  • DrugBank: DB00389 (APRD00503)
  • PubChem: 31072
  • IUPAC: ethyl 3-methyl-2-sulfanylidene-2,3-dihydro-1H-imidazole-1-carboxylate

Additional Details

For the treatment of hyperthyroidism and thyrotoxicosis. It is also used to prepare patients for thyroidectomy.
Carbimazole is a carbethoxy derivative of methimazole. Its antithyroid action is due to its conversion to methimazole after absorption. It is used to treat hyperthyroidism and thyrotoxicosis.
Mode of Action:
Carbimazole is an aitithyroid agent that decreases the uptake and concentration of inorganic iodine by thyroid, it also reduces the formation of di-iodotyrosine and thyroxine. Once converted to its active form of methimazole, it prevents the thyroid peroxidase enzyme from coupling and iodinating the tyrosine residues on thyroglobulin, hence reducing the production of the thyroid hormones T3 and T4.
General Reference:
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1). Any patent infringement and resulting liability is solely at buyer risk.

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