Bromfenac sodium

  • #LGM Pharma is a Bromfenac sodium CAS# 91714-93-1 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, delivery, purity, and more.
  • #Questions? Call our customer API support number 1-(800)-881-8210.
  • #LGM Pharma offers this active ingredient but not the finished dosage forms.

Product Details:

  • CAS No: 91714-93-1
  • AHFC code:
  • Synonyms: AHR 10282B, Bromfenac sodium, Bromsite, Bronuck, UNII-9X8YF771OU
  • ATC Code: S01BC11
  • Chemical Formula: C15-H12-Br-N-O3.Na
  • Molecular Weight: 356.1499
  • Assay/Purity: Typically NLT 98%
  • DrugBank: DB00963
  • SMILES: c1cc(c(c(c1)C(=O)c2ccc(cc2)Br)N)CC(=O)[O-].[Na+]
  • InChl: 1S/C15H12BrNO3.Na/c16-11-6-4-9(5-7-11)15(20)12-3-1-2-10(14(12)17)8-13(18)19;/h1-7H,8,17H2,(H,18,19);/q;+1/p-1
  • PubChem:
  • IUPAC: Benzeneacetic acid, 2-amino-3-(4-bromobenzoyl)-, monosodium salt

Additional Details

Indication:
For the treatment of postoperative inflammation in patients who have undergone cataract extraction.
Pharmacodynamics:
Bromfenac ophthalmic solution is a sterile, topical, nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use.
Mode of Action:
The mechanism of its action is thought to be due to its ability to block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2. Prostaglandins have been shown in many animal models to be mediators of certain kinds of intraocular inflammation. In studies performed in animal eyes, prostaglandins have been shown to produce disruption of the blood-aqueous humor barrier, vasodilation, increased vascular permeability, leukocytosis, and increased intraocular pressure.
Metabolism:
Toxicity:
General Reference:
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1). Any patent infringement and resulting liability is solely at buyer risk.

API’s From Quality Manufacturers:

  • Cost effective materials based on specific requirements
  • Small quantities for initial research and larger development quantities towards product commercialization

 

  • Technical packages, letters of access to filed DMFs
  • Complete assistance in any regulatory filings
  • Top quality GMP certified manufacturers
  • Have necessary regulatory credentials