Amorolfine Hydrochloride

CAS No:
78613-38-4 Categories: , ,
  • #LGM Pharma is a Amorolfine Hydrochloride CAS# 78613-38-4 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, delivery, purity, and more.
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  • #LGM Pharma offers this active ingredient but not the finished dosage forms.

Product Details:

  • CAS No: 78613-38-4
  • AHFC code:
  • Synonyms: Allphar brand of amorolfine hydrochloride, amorolfin hydrochloride, amorolfine, amorolfine hydrochloride, Galderma brand of amorolfine hydrochloride, Isdin brand of amorolfine hydrochloride, Locéryl, Loceryl, Locetar, Odenil, , Ro 14-4767-002, Ro-14-4767-002, Roche brand of amorolfine hydrochloride
  • ATC Code:
  • Chemical Formula: C21H36ClNO
  • Molecular Weight: 353.9744
  • Assay/Purity: Typically NLT 98%
  • DrugBank:
  • SMILES: CCC(C)(C)c1ccc(cc1)CC(C)CN2C[C,H](O[C,H](C2)C)C.Cl
  • InChl: 1S/C21H35NO.ClH/c1-7-21(5,6)20-10-8-19(9-11-20)12-16(2)13-22-14-17(3)23-18(4)15-22;/h8-11,16-18H,7,12-15H2,1-6H3;1H/t16?,17-,18+;
  • PubChem: 54259
  • IUPAC: (2R,6S)-2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine;hydrochloride

Additional Details

Indication:
Amorolfine Hydrochloride is the hyrochloride salt form of amorolfine, a morpholine antifungal agent. Amorolfine inhibits delta-14-reductase and delta-7,8-isomerase, which depletes ergosterol and causes ignosterol to accumulate in the fungal cytoplasmic cell membrane.
Pharmacodynamics:
Mode of Action:
Metabolism:
Toxicity:
General Reference:
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