Aminophylline

  • #LGM Pharma is a Aminophylline CAS# 317-34-0 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, delivery, purity, and more.
  • #Questions? Call our customer API support number 1-(800)-881-8210.
  • #LGM Pharma offers this active ingredient but not the finished dosage forms.

Product Details:

  • CAS No: 317-34-0
  • AHFC code: 26:16.0
  • Synonyms: Aminophyllin Aminophylline Anhydrous Aminophylline Dihydrate Aminophylline Dye Free
  • ATC Code: R03DA05
  • Chemical Formula: C28H31FN4O
  • Molecular Weight: 420.4264
  • Assay/Purity: Typically NLT 98%
  • DrugBank: DB01223 (APRD00329)
  • SMILES: NCCN.CN1C2=C(NC=N2)C(=O)N(C)C1=O.CN1C2=C(NC=N2)C(=O)N(C)C1=O
  • InChl: FQPFAHBPWDRTLU-UHFFFAOYSA-N
  • PubChem: 9433
  • IUPAC: bis(1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione); ethane-1,2-diamine

Additional Details

Indication:
For the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.
Pharmacodynamics:
Aminophylline is the ethylenediamine salt of theophylline. Theophylline stimulates the CNS, skeletal muscles, and cardiac muscle. It relaxes certain smooth muscles in the bronchi through PDE3 inhibition, produces diuresis, and causes an increase in gastric secretion.
Mode of Action:
Theophylline is structurally related to theobromine and caffeine. The precise mechanism of action of theophylline is not known, however, it is thought to be a phosphodiesterase inhibitor which may give a bronchodilatory effect. It also binds adenosine receptors.
Metabolism:
Toxicity:
General Reference:
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1). Any patent infringement and resulting liability is solely at buyer risk.

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