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Product Details:

  • CAS No: 177036-94-1
  • AHFC code:
  • Synonyms: (+-)-(2S)-2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid, Ambrisentan, BSF 208075, BSF-208075, LU 208075, LU-208075, LU208075, Letairis, UNII-HW6NV07QEC, Volibris
  • ATC Code: C02KX02
  • Chemical Formula: C22H22N2O4
  • Molecular Weight: 378.421
  • Assay/Purity: Typically NLT 98%
  • DrugBank:
  • SMILES: c1(ccccc1)C([C,,H](C(=O)O)Oc1nc(cc(n1)C)C)(c1ccccc1)OC
  • InChl: InChI=1S/C22H22N2O4/c1-15-14-16(2)24-21(23-15)28-19(20(25)26)22(27-3,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h4-14,19H,1-3H3,(H,25,26)
  • PubChem: 6918493
  • IUPAC: (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy- 3,3-diphenylpropanoic acid

Additional Details

An ET(A) receptor antagonist; studied for use as in pulmonary arterial hypertension.
Mode of Action:
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