59338-93-1 Category:
  • #LGM Pharma is a Alizapride CAS# 59338-93-1 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, delivery, purity, and more.
  • #Questions? Call our customer API support number 1-(800)-881-8210.
  • #LGM Pharma offers this active ingredient but not the finished dosage forms.

Product Details:

  • CAS No: 59338-93-1
  • AHFC code:
  • Synonyms: Alizaprida [inn-spanish] Alizapridum [inn-latin]
  • ATC Code: A03FA05
  • Chemical Formula: C21H19N3O3S
  • Molecular Weight: 315.3702
  • Assay/Purity: Typically NLT 98%
  • DrugBank: DB01425
  • PubChem: 43008
  • IUPAC: 6-methoxy-N-{[1-(prop-2-en-1-yl)pyrrolidin-2-yl]methyl}-2H-1,2,3-benzotriazole-5-carboxamide

Additional Details

Alizapride is used in the treatment of nausea and vomiting, including postoperative nausea and vomiting.
Alizapride is a dopamine antagonist.
Mode of Action:
The anti-emetic action of Alizapride is due to its antagonist activity at D2 receptors in the chemoreceptor trigger zone (CTZ) in the central nervous system (CNS)ãthis action prevents nausea and vomiting triggered by most stimuli. Structurally similar to metoclopramide and, therefore, shares similar other atributres related to emesis and prokinetics.
General Reference:
Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M: Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial. Cancer Chemother Pharmacol. 1988;22(4):316-20. Pubmed
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